Laboratory for Molecular Immunology
Dr. Aaron James Marshall's research group
WELCOME TO THE MARSHALL LAB
PUBLICATIONS
Elevated expression of interleukin 16 in chronic lymphocytic leukemia is associated with disease burden and abnormal immune microenvironment
Wu X, Thisdelle J, Hou S, Fajardo-Despaigne JE, Gibson SB, Johnston JB, Dawe DE, Banerji V, Marshall AJ.
Dual inhibition of phosphoinositide 3-kinases delta and gamma reduces chronic B cell activation and autoantibody production in a mouse model of lupus
Olayinka-Adefemi F, Hou S, Marshall AJ.
Increased frequency of TIGIT+ CD4 T Cell subset in autoantibody-positive first-degree relatives of patients with rheumatoid arthritis.
Anaparti V, Tanner S, Zhang C, O'Neil L, Smolik I, Meng X, Marshall AJ, El-Gabalawy H.
Critical Roles of Phosphoinositide 3-Kinase δ in the Humoral Immune Response to Trypanosoma congolense Infection.
Olayinka-Adefemi F, Onyilagha C, Jayachandran N, Hou S, Jia P, Uzonna J, Marshall AJ.
J Immunol. 2021 Sep 1;207(5):1401-1410. doi: 10.4049/jimmunol.2100311. Epub 2021 Aug 11.
Altered T Follicular Helper Cell Subsets and Function in Chronic Lymphocytic Leukemia
Wu X, Fajardo-Despaigne JE, Zhang C, Neppalli V, Banerji V, Johnston JB, Gibson SB, Marshall AJ. Front Oncol. 2021 Apr 28;11:674492. doi: 10.3389/fonc.2021.674492. eCollection 2021.
Targeted Therapy for Infectious Disease − A Case for Phosphoinositide 3-Kinase
Adefemi F, Fruman DA, Marshall AJ. J Immunol. 2020 Dec 15;205(12):3237-3245. doi: 10.4049/jimmunol.2000599. PMID: 33288538.
IgA levels at diagnosis predict for infections, time to treatment, and survival in chronic lymphocytic leukemia
Ishdorj G, Streu E, Lambert P, Dhaliwal HS, Mahmud SM, Gibson SB, Banerji V, Marshall AJ, Johnston JB. Blood Adv. 2019 Jul 23;3(14):2188-2198. doi: 10.1182/bloodadvances.2018026591.
Expression and function of phosphoinositide 3-kinase delta in mesenchymal stromal cells from normal and leukaemic bone marrow
Ali AY, Guan Q, Wu X, Hou S, Banerji V, Johnston JB, Wall D, Szwajcer D, Gibson SB, Marshall AJ. Br J Haematol. 2019 Jun;185(5):883-887. doi: 10.1111/bjh.15865. Epub 2019 Mar 14
Distinct roles for phosphoinositide 3-kinases γ and δ in malignant B cell migration.
Ali AY, Wu X, Eissa N, Hou S, Ghia JE, Murooka TT, Banerji V, Johnston JB, Lin F, Gibson SB, Marshall AJ. Leukemia. 2018 Sep;32(9):1958-1969. doi: 10.1038/s41375-018-0012-5. Epub 2018 Jan 31.
TAPP Adaptors Control B Cell Metabolism by Modulating the Phosphatidylinositol 3-Kinase Signaling Pathway: A Novel Regulatory Circuit Preventing Autoimmunity.
Jayachandran N, Mejia EM, Sheikholeslami K, Sher AA, Hou S, Hatch GM, Marshall AJ. J Immunol. 2018 Jul 15;201(2):406-416. doi: 10.4049/jimmunol.1701440. Epub 2018 Jun 8.
Regulation of immune cell signaling by SHIP1: A phosphatase, scaffold protein, and potential therapeutic target.
Pauls SD, Marshall AJ. Eur J Immunol. 2017 Jun;47(6):932-945. doi: 10.1002/eji.201646795. Epub 2017 May 26
FcγRIIB-Independent Mechanisms Controlling Membrane Localization of the Inhibitory Phosphatase SHIP in Human B Cells
Pauls SD, Ray A, Hou S, Vaughan AT, Cragg MS, Marshall AJ. J Immunol. 2016 Sep 1;197(5):1587-96. doi: 10.4049/jimmunol.1600105. Epub 2016 Jul 25