Targeted Therapy for Infectious Disease − A Case for Phosphoinositide 3-Kinase

Adefemi F, Fruman DA, Marshall AJ. J Immunol. 2020 Dec 15;205(12):3237-3245. doi: 10.4049/jimmunol.2000599. PMID: 33288538.

https://pubmed.ncbi.nlm.nih.gov/33288538/

IgA levels at diagnosis predict for infections, time to treatment, and survival in chronic lymphocytic leukemia

Ishdorj G, Streu E, Lambert P, Dhaliwal HS, Mahmud SM, Gibson SB, Banerji V, Marshall AJ, Johnston JB. Blood Adv. 2019 Jul 23;3(14):2188-2198. doi: 10.1182/bloodadvances.2018026591.

https://pubmed.ncbi.nlm.nih.gov/31324639/

Expression and function of phosphoinositide 3-kinase delta in mesenchymal stromal cells from normal and leukaemic bone marrow

Ali AY, Guan Q, Wu X, Hou S, Banerji V, Johnston JB, Wall D, Szwajcer D, Gibson SB, Marshall AJ. Br J Haematol. 2019 Jun;185(5):883-887. doi: 10.1111/bjh.15865. Epub 2019 Mar 14

https://pubmed.ncbi.nlm.nih.gov/30873593/

Distinct roles for phosphoinositide 3-kinases γ and δ in malignant B cell migration.

Ali AY, Wu X, Eissa N, Hou S, Ghia JE, Murooka TT, Banerji V, Johnston JB, Lin F, Gibson SB, Marshall AJ. Leukemia. 2018 Sep;32(9):1958-1969. doi: 10.1038/s41375-018-0012-5. Epub 2018 Jan 31.

https://pubmed.ncbi.nlm.nih.gov/29479062/

TAPP Adaptors Control B Cell Metabolism by Modulating the Phosphatidylinositol 3-Kinase Signaling Pathway: A Novel Regulatory Circuit Preventing Autoimmunity.

Jayachandran N, Mejia EM, Sheikholeslami K, Sher AA, Hou S, Hatch GM, Marshall AJ. J Immunol. 2018 Jul 15;201(2):406-416. doi: 10.4049/jimmunol.1701440. Epub 2018 Jun 8.

https://pubmed.ncbi.nlm.nih.gov/29884706/

Regulation of immune cell signaling by SHIP1: A phosphatase, scaffold protein, and potential therapeutic target.

Pauls SD, Marshall AJ. Eur J Immunol. 2017 Jun;47(6):932-945. doi: 10.1002/eji.201646795. Epub 2017 May 26

https://pubmed.ncbi.nlm.nih.gov/28480512/

FcγRIIB-Independent Mechanisms Controlling Membrane Localization of the Inhibitory Phosphatase SHIP in Human B Cells

Pauls SD, Ray A, Hou S, Vaughan AT, Cragg MS, Marshall AJ. J Immunol. 2016 Sep 1;197(5):1587-96. doi: 10.4049/jimmunol.1600105. Epub 2016 Jul 25

https://pubmed.ncbi.nlm.nih.gov/27456487/

Phosphatidylinositol-3,4-Bisphosphate and Its Binding Protein Lamellipodin Regulate Chemotaxis of Malignant B Lymphocytes.

Li H, Wu X, Hou S, Malek M, Kielkowska A, Noh E, Makondo KJ, Du Q, Wilkins JA, Johnston JB, Gibson SB, Lin F, Marshall AJ. J Immunol. 2016 Jan 15;196(2):586-95. doi: 10.4049/jimmunol.1500630. Epub 2015 Dec 22.

https://pubmed.ncbi.nlm.nih.gov/26695371/

Differential expression and function of CD27 in chronic lymphocytic leukemia cells expressing ZAP-70

Lafarge ST, Hou S, Pauls SD, Johnston JB, Gibson SB, Marshall AJ.Leuk Res. 2015 Jul;39(7):773-8. doi: 10.1016/j.leukres.2015.04.016. Epub 2015 May 2.

https://pubmed.ncbi.nlm.nih.gov/26002513/

ZAP70 expression directly promotes chronic lymphocytic leukaemia cell adhesion to bone marrow stromal cells: Correspondence

Lafarge ST, Li H, Pauls SD, Hou S, Johnston JB, Gibson SB, Marshall AJ. Br J Haematol. 2014 Aug 4

https://pubmed.ncbi.nlm.nih.gov/25088442/

Follicular dendritic cell secreted protein FDC-SP controls IgA production.

Hou S, Landego I, Jayachandran N, Miller A, Gibson IW, Ambrose C, Marshall AJ.
Mucosal Immunol. 2014 Jul;7(4):948-57. doi: 10.1038/mi.2013.113. Epub 2014 Jan 8.

https://pubmed.ncbi.nlm.nih.gov/24399151/